genomic surveillance capacity in low and middle-income countries
a global network of labs with AMR expertise
public health programmes
We are targeting the most relevant pathogen-antibiotic combinations at each collaborating surveillance unit; analysing pathogen sequence data, basic anonymised patient information, and information about how samples were collected. Understanding the changing profile of antimicrobial resistance enables public health programmes to respond accordingly, locally, regionally and ultimately nationally.
Laboratory Infrastructure: Implementing whole genome sequencing of pathogens at laboratories in LMICs.
Training: Providing workshops with the Wellcome Genome Campus Advanced Courses Programme.
Data Infrastructure: Analysis and interpretation through tools developed at the Centre for Genomic Pathogen Surveillance.
Linking genomic and epidemiological surveillance data at a national level, enabling more targeted interventions for infection control for identifying and managing AMR outbreaks once they have occurred and helping prevent further spread.
Sequencing up to 10,000 targeted pathogen samples each year, to characterise populations of AMR bacteria, and understand how these are changing over time.
Data generated by each national unit (collected across an extensive network of sentinel sites) will be shared with the international community.
We will share data as it becomes available through the open platforms PathogenWatch and Microreact developed by the Centre for Genomic Pathogen Surveillance, and through public sequence databases such as the ENA.
Learn more about the GHRU, who we are, and what we’re doing to tackle antimicrobial resistance.
To achieve global surveillance, we’ve established units in the UK, Colombia, India, Nigeria and The Philippines.
Established and leads a network of 125+ laboratories and hospitals in India. Developed molecular methods to identify and type S.pneumoniae and culture clinical samples. Infection Control Committee Chairman, Sentinel Surveillance Programme member and Advisory Board member on antimicrobial resistance
Paediatric infectious disease specialist. Expanded sentinel sites in the Philippines. President of the Paediatric Infectious Disease Society, she founded the Alliance for Prudent Use of Antibiotics, and represented the Philippines to the World Health Organization, Global Salmonella Surveillance, and WHO Gonococcal Resistance Surveillance Programme in the Western Pacific.
Consultant to the Nigerian Centre for Disease Control, Africa CDC, WHO and others. On the Surveillance and Epidemiology of Drug Resistant Infections Consortium advisory board of the Wellcome Trust. Researches antimicrobial resistance, molecular epidemiology, pathogenesis, E. coli, enteric bacteria, applications and uptake of microbiology in Africa; advocating antimicrobial resistance containment.
Public health veterinarian and epidemiologist. Founder of Colombia’s Programme for Integrated Surveillance of Antimicrobial Resistance - an international network establishing baselines for antimicrobial resistance of zoonotic bacteria. Works with the Pan American Health Organization of the WHO.
Dr. John Stelling is an infectious disease specialist in Boston, Massachusetts. He received his medical degree from Johns Hopkins Medical School and has a Master's in Public Health from (MIT) Massachussett's Institute of Technology. Dr. Stelling has been in practice for 29 years.
Senior Group Leader at Big Data Institute, University of Oxford. Within CGPS, provides data and tools for local and international utility, focusing on antimicrobial resistance and genomic surveillance. Examining pathogen surveys, David contextualises WGS datasets and population structure. He identifies important high-risk clones, risk assessment and management.
Learn more about how we envisage developing and learning from our international collaboration.
If you are interested in joining our network of sentinel sites for genomic surveillance of AMR, please contact us via details below.
NIHR Global Health Research Unit
Centre for Genomic Pathogen Surveillance
Wellcome Genome Campus
CB10 1SA UK