We are:
- Building genomic surveillance capacity in low and middle-income countries
- Growing a global network of labs with AMR expertise
- Generating actionable data
- Supporting public health programmes
NIHR Global Health Research Unit
Genomic Surveillance of Antimicrobial Resistance
Bridging genomics, microbiology and big data to tackle global Antimicrobial Resistance (AMR)
Genomic Surveillance of Antimicrobial Resistance
We are targeting the most relevant pathogen-antibiotic combinations at each collaborating surveillance unit; analysing pathogen sequence data, basic anonymised patient information, and information about how samples were collected. Understanding the changing profile of antimicrobial resistance enables public health programmes to respond accordingly, locally, regionally and ultimately nationally.
Capacity Building
Laboratory Infrastructure: Implementing whole genome sequencing of pathogens at laboratories in LMICs.
Training: Providing workshops with the Wellcome Genome Campus Advanced Courses Programme.
Data Infrastructure: Analysis and interpretation through tools developed at the Centre for Genomic Pathogen Surveillance.
National Action
Linking genomic and epidemiological surveillance data at a national level, enabling more targeted interventions for infection control for identifying and managing AMR outbreaks once they have occurred and helping prevent further spread.
Global Open Data
Data generated by each national unit (collected across an extensive network of sentinel sites) will be shared with the international community.
We will share data as it becomes available through the open platforms PathogenWatch and Microreact developed by the Centre for Genomic Pathogen Surveillance, and through public sequence databases such as the ENA.
Structured Pathogen Surveys
Sequencing up to 10,000 targeted pathogen samples each year, to characterise populations of AMR bacteria, and understand how these are changing over time.
Our Background
Learn more about the GHRU, who we are, and what we’re doing to tackle antimicrobial resistance.
Our Locations
To achieve global surveillance, we’ve established units in the UK, Colombia, India, Nigeria and The Philippines.
- Colombia
- India
- Philippines
- Nigeria
- UK
- WHONET
Our Partners
Prof. K.L. Ravikumar
Chief of Central Research Laboratory
KIMS Hospital and Research Centre, Bangalore
India
Established and leads a network of 125+ laboratories and hospitals in India. Developed molecular methods to identify and type S.pneumoniae and culture clinical samples. Infection Control Committee Chairman, Sentinel Surveillance Programme member and Advisory Board member on antimicrobial resistance
Dr. Celia Carlos
Director
Research Institute for Tropical Medicine
Philippines
Paediatric infectious disease specialist. Expanded sentinel sites in the Philippines. President of the Paediatric Infectious Disease Society, she founded the Alliance for Prudent Use of Antibiotics, and represented the Philippines to the World Health Organization, Global Salmonella Surveillance, and WHO Gonococcal Resistance Surveillance Programme in the Western Pacific.
Prof. Iruka Okeke
Professor of Pharmaceutical Microbiology
University of Ibadan
Nigeria
Consultant to the Nigerian Centre for Disease Control, Africa CDC, WHO and others. On the Surveillance and Epidemiology of Drug Resistant Infections Consortium advisory board of the Wellcome Trust. Researches antimicrobial resistance, molecular epidemiology, pathogenesis, E. coli, enteric bacteria, applications and uptake of microbiology in Africa; advocating antimicrobial resistance containment.
Dr Pilar Donado-Godoy
Lead Investigator
Colombian Agriculture Research Corporation
Colombia
Public health veterinarian and epidemiologist. Founder of Colombia’s Programme for Integrated Surveillance of Antimicrobial Resistance – an international network establishing baselines for antimicrobial resistance of zoonotic bacteria. Works with the Pan American Health Organization of the WHO.
Dr John Stelling
Co-Director of WHONET
Brigham and Women’s Hospital, Boston
WHONET
Dr. John Stelling is an infectious disease specialist in Boston, Massachusetts. He received his medical degree from Johns Hopkins Medical School and has a Master’s in Public Health from (MIT) Massachussett’s Institute of Technology. Dr. Stelling has been in practice for 29 years.
Prof. David Aanensen
Director
Centre for Genomic Pathogen Surveillance
UK
Senior Group Leader at Big Data Institute, University of Oxford. Within CGPS, provides data and tools for local and international utility, focusing on antimicrobial resistance and genomic surveillance. Examining pathogen surveys, David contextualises WGS datasets and population structure. He identifies important high-risk clones, risk assessment and management.
Meet Our Partners
Learn more about how we envisage developing and learning from our international collaboration.
The GHRU Consortium
The Centre for Genomic Pathogen Surveillance
David Aanensen
Lead PI Central Hub, and Director of The GHRU
Lucy Matkin
Project Manager
Ben Pascoe
Head of Laboratory Implementation
Emmanuelle Kumaran
Digital Epidemiologist
Paul Carvalho
GFGP Consultant
Natacha Couto
Consultant Bioinformatician
Ali Molloy
Independent Consultant
Anneke Schmider
Independent Consultant
Carolin Vegvari
Independent Consultant
The Centre for Genomic Pathogen Surveillance
Celia Carlos
Director, Philippines National Surveillance Unit
Sonia Sia
Head of the Antimicrobial Resistance Reference Laboratory
Elmer M. Herrera
Chief, Finance Division/Financial and Management Officer
Marietta Lagrada
Senior lab scientist / microbiologist
Polle K. Macaranas
Lab scientist / microbiologist
Agnettah M. Olorosa
Lab scientist / microbiologist
June Gayeta
Bioinformatician
Melissa Ana Masim
Bioinformatician
Karis Lee Del Castillo – Boehme
Project Coordinator
Laila Flores
PA to Dr Celia Carlos
The Centre for Genomic Pathogen Surveillance
K. L. Ravikumar
Director, India National Surveillance Unit
Geetha Nagaraj
Associate Professor / Project Coordinator
Varun Shammana
Senior Bioinformatician
Vandana Govindan
WHONET
Muthumeenakshi Bhaskaran
Research Associate
Ravishankar K.N
Manager- Accounts
The University of Ibadan, College of Medicine
Iruka N Okeke
Co-Lead PI, NIHR GHRU, and Director, Nigeria National Surveillance Unit
Grace O. Oparinde
Lab scientist
Jolaade J Ajiboye
Project Coordinator / Admin Support
Ayodele Akinyele
Finance Officer / Admin Support
Elizabeth T Akande
Bioinformatician / PhD Student
El-shama Q Nwoko
Bioinformatician / PhD Student
Abeeb Adeniyi
Digital Epidemiologist
AGROSAVIA, Colombian Agriculture Research Corporation
María del Pilar Donado Godoy
Director, Colombia National Surveillance Unit
Johan Fabian Bernal Morales
Bioinformatician
Maria Fernanda Valencia Guerrero
Lab scientist / microbiologist
Erik Cristopher Dustin Osma Castro
Project and Finance Coordinator/Administrative Professional
Gabriel Beltrán
Bacteriologist
Xavier Fargetton
Strategic Development Expert
Felipe Delgadillo
Microbiologist and Biologist
Join Us
If you are interested in joining our network of sentinel sites for genomic surveillance of AMR, please contact us via details below.
Contact Details
NIHR Global Health Research Unit
Centre for Genomic Pathogen Surveillance
Old Road Campus,
University of Oxford
OX3 7LF
+44(0)1223 495356
[email protected]
Partner Institutions
KIMS Hospital and Research Centre, Bangalore
Research Institute for Tropical Medicine
University of Ibadan
Colombian Agriculture Research Corporation
WHONET
Centre for Genomic Pathogen Surveillance
